Skin is the largest sense organ in the human body, covering approximately 1.5-2 square meters in adults. It contains sensory receptors for touch, pressure, pain, temperature, and vibration - making it our largest sensory interface with the external environment. The eye (vision), ear (hearing/balance), and nose (smell) are specialised sense organs but much smaller in surface area. Skin also has additional functions: protection, thermoregulation, vitamin D synthesis, and immune surveillance.