Multiple choice

Reye's syndrome is ultrastructurally characterized by

  1. mitochondrial blebs and enlarged mitochondria

  2. depletion of glycogen

  3. dilatation of the endoplasmic reticulum

  4. perinuclear staining
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Reye's syndrome is characterized ultrastructurally by mitochondrial injury manifesting as mitochondrial blebs and enlarged mitochondria with disrupted cristae. This reflects the mitochondrial dysfunction central to the pathophysiology. Glycogen depletion (option B) is a nonspecific finding seen in many metabolic conditions. ER dilation and perinuclear staining are not characteristic ultrastructural features of Reye's syndrome.

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