Optic pathway gliomas (including optic nerve and optic tract gliomas) are the most common tumors associated with Neurofibromatosis type 1 (NF-1), occurring in 15-20% of patients. They are typically low-grade pilocytic astrocytomas. While astrocytomas can occur in NF-1, the optic pathway glioma is the most characteristic and frequent. Glioblastoma is not associated with NF-1.