Multiple choice

Which of the following is false regarding phenytoin?

  1. It induces microsomal enzymes.

  2. At very low doses, zero order kinetics occurs.

  3. Higher the dose, higher is the half life.

  4. Highly protein bound.
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Phenytoin follows FIRST-order kinetics at therapeutic doses, not zero-order. Zero-order kinetics occurs at HIGH doses (saturation of metabolism), not low doses. The statement is backwards. Phenytoin does induce microsomal enzymes, shows dose-dependent half-life increase, and is highly protein-bound.

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