Multiple choice

Which of the following is not true about fibrates?

  1. (MOA)__ Apa_ lipoprotein lipase_decreased LDL_

  2. Absorbed better on empty stomach and decreased on food intake.

  3. Side effects include rash, myalgia, impotence and many others.

  4. They are the drug of choice in type III hyperlipidemia and hypertriglyceridemia
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Fibrates are actually better absorbed WITH food to enhance bioavailability and reduce GI side effects. The statement claiming better absorption on empty stomach is false. Fibrates activate PPAR-alpha, increase lipoprotein lipase activity, and are indeed first-line for type III hyperlipidemia and hypertriglyceridemia.

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