Multiple choice

Assertion (A): Zinc-finger nucleases (ZFNs) are artificial restriction enzymes. Reason (R): The DNA-binding domains of individual ZFNs typically contain between nine and eighteen individual zinc finger repeats.

Directions: In the following question there are two statements, Assertion (A) and Reason (R), consider both the statements independently and mark your answers as under:
1. If A and R both are correct and R is correct explanation of A.
2. If A and R both are correct and R is not correct explanation of A.
3. If A is correct and R is incorrect.
4. If A is incorrect and R is correct.
5. If A and R both are incorrect.

  1. 1

  2. 2

  3. 3

  4. 4

  5. 5
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

A is correct whereas R is incorrect. Zinc-finger nucleases are artificial restriction enzymes obtained by fusing a zinc finger DNA-binding domain to a DNA-cleavage domain. The DNA-binding domains of individual ZFNs typically contain between three and six individual zinc finger repeats and can each recognise between 9 and 18 base pairs.

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