Multiple choice

Which of the following statements does NOT characterise organisms as genetically engineered organisms containing recombinant DNA?

  1. Western hybridisation methods can be used to detect RNA and/or protein products.

  2. Recombinant DNA can have beneficial effects even if it is not expressed.

  3. The organisms containing recombinant DNA have apparently normal phenotypes.

  4. Additional phenotypes that are encountered include toxicity to the host organism.

  5. Inappropriate activation of previously unexpressed host cell genes can insert rDNA into chromosomal DNA.

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

In some cases, recombinant DNA can have deleterious effects even if it is not expressed. One mechanism by which this happens is insertional inactivation, in which the rDNA becomes inserted into a host cell's gene.