Multiple choice

After complete medical checkup, a doctor told a couple that their daughter is suffering from a severe viral disease in which the oligodendrocytes, the myelinating cells of the central nervous system are damaged. Which of the following diseases is the doctor referring to?

  1. Progressive multifocal leukoencephalopathy (PML)

  2. Subacute sclerosing panencephalitis (SSPE)

  3. Progressive rubella panencephalitis (PRP)

  4. Scrapie

  5. Kuru
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A Correct answer
Explanation

This is a rare, progressive, fatal, demyelinating disease of the CNS that kills oligodendrocytes. It results in memory loss, loss of co-ordination, mentation problems, vision problems, etc. The disease is caused by certain members of the polyomavirus family, usually JC virus.

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