Multiple choice Which pair of chemicals would prevent the formation of microtubules in cytoplasm? Nicotine and cyanide Ricin and cocavalin Rotenone and vinchristine Colchicine and vinblastin Oubain and ricin Reveal answer Fill a bubble to check yourself D Correct answer Explanation Colchicine inhibits microtubule polymerization by binding to tubulin, one of the main constituents of microtubules. Vinblastine is an antimicrotubule drug used to treat certain kinds of cancer.