Multiple choice

Which of the following viral diseases can be cured by amantadine?

  1. Genital herpes

  2. Dengue

  3. Influenza

  4. Yellow fever
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Amantadine can cure influenza. The mechanism of antiviral activity of amantadine involves interference with the viral protein, M2, a proton channel. Resistance to the drug class is a consequence of mutations to the pore-lining residues of the channel, leading to the inability of the sterically bulky adamantane ring that both share in entering in their usual way, into the channel.

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