Multiple choice

The main side effect of excessive intake of “Acetaminophen” is

  1. nausea

  2. abdominal pain

  3. haemoptysis

  4. liver failure

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D Correct answer
Explanation

Excessive intake of acetaminophen (paracetamol) causes liver failure (hepatotoxicity) as its main serious side effect. In overdose, the normal metabolic pathways become saturated, leading to formation of the toxic metabolite NAPQI which causes liver necrosis. Nausea and abdominal pain can occur but are not the main serious effect. Haemoptysis is not associated with acetaminophen toxicity.

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