Calcitonin LOWERS plasma calcium levels by inhibiting bone resorption (osteoclast activity) and increasing calcium excretion by kidneys. It also lowers plasma phosphate. The question asks for the 'odd one out' - option A claims calcitonin raises calcium, which is incorrect and therefore the exception. However, the phrasing is confusing since calcitonin doesn't do any of these directly - it inhibits bone resorption which indirectly lowers calcium.