Multiple choice

Ribonuclease A is a digestive enzyme secreted by the pancreas. The inhibitor(s) for ribonuclease A is/are

P. Pb2+ Q. Hg+ R. Uridine-vanadate complex S. Acetyl-coA

  1. Only R

  2. Both P and Q

  3. Both Q and R

  4. Both R and S

  5. All P, Q and R
Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

Correct answer. Ribonuclease A (RNase A) is a small (124 amino acids) digestive enzyme secreted by the pancreas and is an endonuclease specifically designed to hydrolyse RNA phosphodiester bonds which covalently link ribonucleotides particularly those linked to pyrimidine bases such as uracil. It can be inhibited by ribonuclease inhibitor protein, by heavy metal ions (like Pb2+, Hg+  etc.), and by uridine-vanadate complexes.

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