Directions: The question below consists of a word, followed by four words or phrases. Choose the word or phrase that is closest in meaning to the given word.

Alienate

To alienate means to cause someone to feel isolated or estranged from a group or person. 'Estrange' is the perfect synonym as it specifically means to cause someone to become distant or separated in feeling. The other options are incorrect: 'illness' and 'eagerness' are unrelated, while 'associate' has the opposite meaning (to connect rather than separate).