Multiple choice

A nasal spray containing adenovirus carrying a functional human CFTR gene is used to treat cystic fibrosis. This is an example of ____ gene therapy.

  1. in situ

  2. in vivo

  3. ex vivo

  4. vaccine

  5. germ line
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

In vivo gene therapy delivers genetic material directly into the patient's body. This nasal spray delivers the CFTR gene directly to lung epithelial cells via adenovirus vectors, compensating for the defective gene in cystic fibrosis patients. This contrasts with ex vivo therapy, where cells are modified outside the body before reinfusion.

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