Multiple choice

When tryptophan is present in the environment of E. coli, the tryptophan binds to the

  1. trp operon

  2. trp promoter

  3. trp operator

  4. trp repressor

  5. trp polymerase

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

When tryptophan is abundant in the environment, it acts as a corepressor by binding to the trp repressor protein. This binding changes the repressor's conformation, allowing it to bind to the trp operator and block transcription of the tryptophan biosynthesis genes. This is negative feedback regulation.