Multiple choice

The reagent used in the Oseltamivir total synthesis is

  1. trimethyl orthoformate

  2. trimethylsilyl azide

  3. trimethylsilyl chloride

  4. trimethylsilyldiazomethane
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

It is considered as a safer replacement for hydrazoic acid in many reactions. It will however over time hydrolyze to hydrogen azide and therefore it must be stored free of moisture. It is used in the Oseltamivir total synthesis.

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