Multiple choice

Isoelectric pH of leucine is

  1. 5

  2. 5.2

  3. 5.8

  4. 6.0
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D Correct answer
Explanation

The isoelectric pH (pI) of leucine is approximately 6.0. This is calculated as the average of its carboxyl group pKa (~2.4) and amino group pKa (~9.6), giving pI = (2.4 + 9.6)/2 = 6.0. At this pH, leucine exists as a zwitterion with no net charge.

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