The Huna (Hephthalite) invasions, particularly under Toramana and Mihirakula in the late 5th and early 6th centuries CE, severely weakened the Gupta Empire and contributed to its decline. These Central Asian invaders repeatedly attacked northern India, disrupting trade, administration, and stability. While options C and D name specific Huna rulers, option A correctly identifies the Huna people as the invading force that led to the empire's end. The question structure is slightly flawed since Toramana and Mihirakula were themselves Huna rulers, but 'Huna invasions' is the historically accurate term.