Multiple choice Animalcule, a microbial organism, was observed using a single-lens microscope by Christian Gottfried Ehrenberg Carl Woese Louis Pasteur Antonie van Leeuwenhoek Robert Koch Reveal answer Fill a bubble to check yourself D Correct answer Explanation Bacteria were first observed by Antonie van Leeuwenhoek in 1676, using a single-lens microscope of his own design. He called them 'animalcules' and published his observations in a series of letters to the Royal Society.