Monosubstituted benzene when treated with an electrophile, undergoes electrophilic aromatic substitution reactions. Each reaction yields disubstituted benzene as the product, which can be identified using the descriptors ortho, para and meta as products.
Common ortho and para directing groups are:
-OH, -OCH3, -NR2, -CH3, -NR2 etc.
Common meta directing groups are:
-NO, -SO3H, -COCH3, -CHO, -NO2, -CN, -NR3+ etc.
Hence, only –OCH3 group is ortho and para directing.