Multiple choice

Mycobacterium is a genus characterized by various pathogenic bacteria. Granuloma formation in mycobacterial infection does NOT include which of the following processes?

  1. Engulfment of the mycobacteria by the macrophages

  2. Replication of the mycobacteria within the phagosomes

  3. Production of IL-12 to drive Th1 differentiation of immature CD4 cells

  4. TNF-α production for activation of macrophages to epithelioid forms

  5. Production of IL-4

Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

Production of IL-4 by Th2 cells is not a part of granuloma formation, which involves Th1 activation rather than Th2 activation.