Multiple choice

In mammals, the maternal changes in the kidney during pregnancy includes _____________.

  1. decrease in urine flow through the collecting system

  2. decrease in glomerular filtration rate

  3. decrease in creatinine clearance

  4. decrease in size

  5. decrease in water sodium absorption
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A Correct answer
Explanation

Urine flows more slowly through the maternal renal collecting system due to dilatation of the ducts. This dilatation is the result of mechanical obstruction by the enlarging uterus along with the relaxing effects of progesterone on smooth muscle.

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