Multiple choice

MIS or Müllerian inhibiting substance, is a peptide secreted under the direction of SRY (the sex-determining region of the Y chromosome). It is secreted by which cells?

  1. Sertoli cells

  2. Leydig cells

  3. Metanephric kidneys

  4. Mullerian duct epithelium

  5. Germ cells

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A Correct answer
Explanation

Those testicular cells destined to become Sertoli cells will secrete MIS under the direction of SRY and cause the Müllerian ducst to degenerate.