Multiple choice

TMS is the most suitable reference compound for NMR spectroscopy. However, it cannot be used with deuterium oxide solvent because:

  1. it is highly volatile
  2. it is chemically inert
  3. it is magnetically isotropic
  4. it is insoluble in deuterium oxide

  1. Only 1

  2. Only 2

  3. Only 2 and 3

  4. Only 3 and 4

  5. Only 4
Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

This option is correct because chemical inertness, magnetically isotropic nature and high volatility of tetramethylsilane (TMS) makes is reference compound of choice for NMR studies. Because of its insolubility in deuterium oxide, it cannot be used with this solvent.

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