Multiple choice

Which of the following conditions occurs in holoprosencephaly?

  1. Embryonic forebrain fails to divide the brain into two lobes.

  2. Cerebral hemispheres are absent.

  3. Complete absence of cerebral cortex.

  4. Abnormal accumulation of cerebrospinal fluid.
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A Correct answer
Explanation

In holoprosencephaly, embryonic forebrain fails to divide into two lobes. In most cases of holoprosencephaly, the malformations are so severe that babies die before birth.

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