Multiple choice

With reference to the properties of sugars in DNA, answer the following question.

What would be the expected change in the DNA structure if the 1' position of the deoxyribose sugar is silenced?

  1. The double helical structure will distort and bend towards right.

  2. The complete double helical structure will be destroyed.

  3. The stack space will be highly decreased thus minimising the helical rise.

  4. There would not be a visible change in the structure although physico-chemical properties would be affected.
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

The deoxyribose sugar has an 'H' instead of 'OH' at 2' position. The nitrogenous bases binds to the 1' position of the sugars by glycosidic bonds. Silencing of the 1' position will hinder the glycosidic bond formation and thereby disrupting the complete structure.

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