Directions: The process by which enzymes are converted to inactive substances with the help of compounds thereby severely affecting the enzymatically catalysed reaction rate is called enzyme inhibition.

Sulpha drugs play an important role in the metabolism of p-amino benzoic acid. These drugs follow the standard of

Antibacterial drugs like sulpha drugs are competitive inhibitors which play an important role in the metabolism of p-amino benzoic acid or PABA. Bacteria synthesise folic acid from p-amino benzoic acid. Sulpha drugs are structurally similar to PABA and therefore sulpha drugs behave as the enzyme inhibitor and are placed at the enzyme’s active site.