Multiple choice

All of the following physiological processes occur during the growth at the epiphyseal plate, except

  1. proliferation and hypertrophy

  2. calcification and ossification

  3. vasculogenesis and erosion

  4. replacement of red bone marrow with yellow marrow
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D Correct answer
Explanation

At the epiphyseal growth plate (physes) new bone growth occurs by the process of enchondral ossification, i.e. ossification of proliferating cartilage. This process sequentially involves proliferation and hypertrophy of chondrocytes, their calcification and vascular invasion. Replacement of red bone marrow with the white marrow is not seen.

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