Multiple choice

'Angiogenesis' is a physiological process involving the growth of new blood vessels from pre-existing vessels. Which of the following inhibits angiogenesis?

  1. VEGF

  2. FGF 2

  3. Interleukin-6

  4. Angiostatin

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

'Angiostatin' is endogenously produced in the tumor 'stroma'. Therefore, the circulating levels can control metastatic cell proliferation until a primary tumor is removed. Angiostatin inhibits angiogenesis.