If the goal were to create a plant resistant to an insecticide, which cell-based plant technology would be most effective?

Mutant selection involves growing plant cell cultures in vitro and screening for mutants with desired traits (like insecticide resistance). Selected mutant cells can then be regenerated into whole plants. Clonal propagation produces genetically identical copies. Cybridization combines cytoplasm from one species with nucleus of another. Protoplast fusion combines whole genomes.