Which of the following enzymes acts on the aldehyde or oxo group of donors?
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Pyruvate dehydrogenase
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Alcohol dehydrogenase
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NADH dehydrogenase
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Malate dehydrogenase
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Glycerol dehydrogenase
A
Correct answer
Explanation
Pyruvate dehydrogenase belongs to Category EC 1.2 of oxidoreductases (EC 1), which act on the aldehyde or oxo group of donors.
Pyruvate dehydrogenase performs the first two reactions within the pyruvate dehydrogenase complex: decarboxylation of pyruvate and reductive acetylation of lipoic acid.