Multiple choice

Which antibodies could be detected on day 18 in both the strains of mice?

Directions: In an experiment on immune response of mice to allergens, dust mice allergen was exposed to two strains of mice – BALB/c mice (B) and Nude mice (N). The allergen was administered on day 0 and day 8 to both the strains of mice and allergen specific antibody produced was monitored and studied.

  1. Ig G (B) and Ig M (N)

  2. Ig E (B) and Ig E (N)

  3. Ig E (B) and Ig D (N)

  4. Ig A (B) and Ig G (N)

  5. both 2 and 3
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A Correct answer
Explanation

On day 8, the allergen was again administered and thus it will create sensitization, resulting in release of the most predominant antibody Ig G, in case of BALB/c mice. The same will persist in case of nude mice.

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