Multiple choice

Heme is converted to bilirubin mainly in

  1. kidney

  2. liver

  3. spleen

  4. bone marrow
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Breakdown of heme to bilirubin occurs in macrophages of the reticulo-endothelial system. Major sites of bilirubin production are spleen and other compartments of reticuloendothelial system, which degrade the haemoglobin of injured RBCs. Other sites are liver and bone marrow.

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