Which of the following is a pair of exclusively ketogenic amino acids?
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Leucine and Isoleucine
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Leucine and Lysine
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Lysine and Tyrosine
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Isoleucine and Lysine
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Leucine and Tyrosine
B
Correct answer
Explanation
A significant amount of metabolic energy can come from amino acid metabolism, particularly under conditions of starvation. Amino acids that are metabolized to produce acetyl-CoA and acetoacetate are called ketogenic amino acids. In humans, two amino acids are exclusively ketogenic: Leucine and Lysine.