Multiple choice

The bridge-fragment configuration at anaphase-1 is characteristic of

  1. translocation heterozygote

  2. paracentric inversion heterozygote

  3. pericentric inversion heterozygote

  4. duplication heterozygote
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B Correct answer
Explanation

During anaphase I in paracentric inversion heterozygotes, a bridge-fragment configuration forms because crossing over within the inversion creates a dicentric chromosome (forms a bridge) and an acentric fragment (lacks a centromere). Translocation heterozygotes form quadrivalents, pericentric inversions don't produce this pattern, and duplications don't create bridges.

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