Multiple choice

A research student viewing a PDB structure in PyMol concludes that the protein is surely involved in dimer formation but further inferred that it does not involve in any direct interaction with DNA. Which of the following clues helps you infer the same?

  1. Zinc finger

  2. Helix-turn-helix

  3. Homeodomain

  4. Leucine zipper

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Leucine zippers are exclusively involved in protein-protein dimerization, while they ineract with DNA’s sugar and phosphate molecules in an induced way, rather than direct binding.