Multiple choice

“Inhibition of the prokaryotic transcription is caused by rifampin, an antibiotic.” Which of the following options is correct for rifampin action?

  1. Binds with the β-subunit of prokaryotic RNA polymerase.

  2. Binds with RNA polymerase II.

  3. Binds with DNA template and blocks movement of RNA polymerase.

  4. Binds with promoter region.

  5. None of the above

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A Correct answer
Explanation

Rifampin is an antibiotic that is widely used for the treatment of tuberculosis and leprosy. It binds with the β-subunit of prokaryotic RNA polymerase and inhibits the movement of the enzyme and its activity.

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