Multiple choice

Match the following: Column A Column B P. PCNA i. Single strand binding protein Q. RPA ii. Prevent continuous DNA loss at the end of Chromosome R. Telomeres iii. Fragmented DNA produced on the lagging strand S. Okazaki fragments iv. Leading strand synthesis

  1. P - ii, Q - i, R - iii, S - iv

  2. P - iii, Q - i, R - iv, S - ii

  3. P - iv, Q - i, R - ii, S - iii

  4. P - ii, Q - iv, R - iii, S - i

  5. P - iii, Q - iv, R - i, S - ii
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C Correct answer
Explanation

Proliferating cell nuclear antigen (PCNA) along with DNA polymerase δ helps in leading strand synthesis. Replication protein A (RPA) is a single strand binding protein. Telomeres are the special structures that prevent continuous DNA loss at the end of chromosome. The fragmented DNA produced during the lagging strand synthesis is Okazaki fragment.

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