Multiple choice

While playing Mudit accidentally ingested a chemical and presented with high fever. The chemical is known to affect ATP formation in electron transport chain. Which of the following could cause similar manifestations?

  1. Rotenone

  2. 2,4-Dinitrophenol

  3. Antimycin A

  4. Cyanide

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

It  is a chemical uncoupler of electron transport and oxidative phosphorylation. It permeabilizes the inner mitochondrial membrane to protons, killing the proton gradient . In this situation, electrons continue to pass through the electron transport system and reduce oxygen to water, but ATP is not synthesized in the process thus it produces similar manifestations as given in the above question.