Match column – I (Disease) with column – II (Target tissues for gene therapy) and select the correct option.
| |
|
| Column – I |
Column – II |
| A. Haemophilia b |
1. Synovial membrane |
| B. Cystic fibrosis |
2. Respiratory epithelium |
| C. Rheumatoid arthritis |
3. Skin fibroblasts |
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A - 1, B - 2, C - 3
-
A - 2, B - 1, C - 3
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A - 3, B - 2, C - 1
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A - 2, B - 3, C - 1
-
A - 3, B - 1, C - 2
C
Correct answer
Explanation
Correct answer.
Respiratory epithelial cells are target tissues for gene therapy for the treatment of respiratory insufficiency in cystic fibrosis.
Skin fibroblasts are target tissues for gene therapy for the treatment of haemophilia b.
Synovial membrane (the soft tissue found between the articular capsule and the joint cavity of synovial joints) are target tissues for gene therapy for the treatment of rheumatoid arthritis.