The proximal convoluted tubule (PCT) is the primary site of glucose reabsorption in the nephron. Nearly 100% of filtered glucose is reabsorbed here via sodium-glucose cotransporters (SGLT2 and SGLT1) and GLUT transporters. The Bowman's capsule is the filtration site, loop of Henle concentrates urine, and distal convoluted tubule handles fine-tuning of electrolyte balance.