Multiple choice

Which fungal metabolite disrupts the structure and function of Golgi apparatus?

  1. L-741,494

  2. Brefeldin A

  3. Ciclosporin

  4. Fumonisin

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus by inhibiting transport of proteins from ER to Golgi and inducing retrograde protein transport from the Golgi apparatus to the endoplasmic reticulum.