Multiple choice The structural component of HIV required for cell -cell fusion is gp 120 gp 41 p24 P2 protein Reveal answer Fill a bubble to check yourself B Correct answer Explanation For the HIV infection to occur, the cell fusion is essential. This is done by the trans-membrane glycoprotein gp 41. HIV-1 utilises two major co-receptors along with CD4 to bind to, fuse with and enter target cells.