Multiple choice

Which of the following statements regarding prepost clinical trial is most appropriate?

  1. They cannot be randomized.

  2. They are useful in studies involving mortality.

  3. They use the patient as his or her own control.

  4. They are usually easier to interpret than the comparable parallel clinical trial.

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Prepost clinical trials centre on comparing the incidence of disease before and after introduction of a preventing measure. The events that took place prior to the use of the new treatment or preventive procedure are used as a standard for comparison. The experiment serves as its own control; eliminates virtually all group differences.