Apoptosis is a precisely regulated, programmed cell death process characterized by cell shrinkage, chromatin condensation, DNA fragmentation, and formation of apoptotic bodies without inflammation. It is fundamentally different from necrosis (A), which is uncontrolled cell death resulting from injury, causing membrane rupture and inflammation. Cell cycle arrest (D) may precede apoptosis but is not its defining feature. Membrane leaky syndrome (C) is not a standard biological term and does not describe apoptosis. Option B correctly identifies apoptosis as programmed cell death.