Multiple choice What happens in a tautomeric shift? Adenine and guanine are changed and can no longer form base pairs. The purines chemically get mutated to pyrimidines. Hydrogen atoms move from one position to another position. Carbon atoms move to form a base with altered properties. Reveal answer Fill a bubble to check yourself C Correct answer Explanation In tautomeric shift, hydrogen atoms move from one position in a purine or pyrimidine to another position; for example, from an amino group to a ring nitrogen.