The minerals required in large quantities (macrominerals) by humans include calcium, phosphorus, sodium, magnesium, potassium, and sometimes sulfur and chloride depending on classification system. Option C (phosphorus, calcium, sodium, magnesium) contains four well-established macrominerals. The other options mix major and trace minerals - zinc, molybdenum, manganese, cobalt, and copper are all trace minerals needed in much smaller amounts, while nitrogen is an element obtained from organic compounds rather than as a mineral nutrient.