Multiple choice

At a particular locus, frequency of ‘A’ allele is 0.6 and that of ‘a’ is 0.4. What would be the frequency of heterozygotes in a random mating population at equilibrium?

  1. 0.24

  2. 0.16

  3. 0.48

  4. 0.36

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C Correct answer
Explanation

  The genotype proportions p2, 2pq, and q2 are called the Hardy-Weinberg proportions.Two alleles denoted A and a with frequencies f(A) = p and f(a) = q, respectively,Expected genotype frequencies are-  f(AA) = p2 for the AA homozygotes,  f(aa) = q2 for the aa homozygotes, and f(Aa) = 2pq for the heterozygotes. So, the frequency of heterozygotes = 2pq= 2 X 0.6 X 0.4 = 0.48