This is an interleaved pattern with two separate sequences. Even-positioned terms (2nd, 4th, 6th, ...): -3, -9, -15, ? follow the pattern subtracting 6 each time (-9 = -3 - 6, -15 = -9 - 6). Continuing: -15 - 6 = -21, then -21 - 6 = -27, then -27 - 6 = -33. Odd-positioned terms (1st, 3rd, 5th, ...): 4, 24, 124, 624, 3124 follow a pattern where each term is 5 times the previous odd term plus 4. The negative number after 3124 is -33.